A total of 19 aging-related genes were kidney cancer DEGs: ABCG8, ADGRV1, CDH3, CGA, CPAMD8, CRISP2, DNER, ERP27, GABRP, LHFPL4, OR2I1P, PAPPA2, PCSK9, S100A2, SCEL, SLC16A5, STAP1, TMPRSS4, and UBD. The gene discussed is TMPRSS4; the disease is kidney cancer.