When cardiomyocytes are stressed, Brg1 expression increases, forms a complex with HDAC/PARP, and outruns the inhibitory effect of Mhrt779 so that it can inhibit myh6 and promote expression of myh7 promoting hypertrophy; and inhibition of Mhrt779 prevented experimental cardiac hypertrophy in mice [122]. Here, MYH7 is linked to cardiac hypertrophy.