SOD1 and amyotrophic lateral sclerosis: In line with data concerning the motor cortex of SOD1 mutation-bearing ALS patients in which the overall number of microglia cells does not change [15], we did not observe a different number of Iba1-positive cells in hSOD1G93A transgenic mice compared to WT ones (WT 175.1 ± 3.7 vs. 185.7 ± 5.8 in hSOD1G93A; Figure 1B,C).