IFNB1 and infection: In a similar set of experiments, AMs obtained from control, D. pigrum 040417- and D. pigrum 030918-treated infant mice were challenged in vitro with S. pneumoniae serotype 3, and the levels of IFN-β, IFN-γ, IL-10, and IL-27 in culture supernatants were assessed 24 h post-infection (Figure 7B).