While wbPSMA-TV and wbTL-PSMA were significant predictors of progression-free survival (PFS) in this heterogenous cohort of newly diagnosed PC patients, with only 30 being metastatic and none treated with PSMA-RLT, their value in monitoring treatment and predicting OS specifically after PSMA-RLT remains to be elucidated [10]. This evidence concerns the gene FOLH1 and pachyonychia congenita.