SHKBP1 and neoplasm: It was shown that such a h-k-SOI-NW chip with immobilized oDNA analogues of circ-SHKBP1–probes can be effectively employed in the detection of complementary oDNAs with high concentration sensitivity (detection limit (DL) ~10−16 M) and in the detection of circRNA in blood plasma patients diagnosed with neoplasm of uncertain nature of the brain and central nervous system.