FGF1 and metabolic disease: FGF1 belongs to the FGF family, which is involved in several pathological conditions such as metabolic disorders, participates in the regulation of physiological processes such as the development, angiogenesis, adipogenesis and neurogenesis of the CNS, performs basic functions during embryonic development [134] and is involved in processes such as proliferation, adhesion, differentiation, survival, apoptosis, neuronal plasticity and cell motility [135].