Among these regulators, the expression levels of YTHDF3, YTHDF2, KIAA1429, HNRNPA2B1, RBM15, METTL3, HNRNPC, YTHDF1, IGF2BP2, IGF2BP3, and IGF2BP1 in LUAD tumor tissues were significantly higher than those in normal tissues, while FTO, ZC3H13, WTAP, and METTL14 were lower than in normal tissues. The gene discussed is YTHDF2; the disease is neoplasm.