The 6-hydroxydopamine (6-OHDA) induced Parkinson-like model in male rats was studied by them, who reported that treatment with nanoquercetin prevented the disruption of memory while increasing antioxidant enzymatic activities such as SOD and catalase decreased the Malondialdehyde (MDA) level in the hippocampal area of the brain, thus supporting their provided hypothesis of using quercetin as an anti-Parkinson agent in rats [153]. This evidence concerns the gene SOD1 and Parkinsonism.