BRCA1 and breast carcinoma: In comparison to non-carriers, BRCA1/2 carriers were more likely to have early onset breast cancer (48% versus 28%, p = 0.05), to be premenopausal at the time of diagnosis (82% vs. 54%, p = 0.02), and to have family history of breast cancer (45% vs. 35%, p = 0.024).