In recent years, a milieu of inflammatory factors, cytokines and chemokines have been found to be useful in immune diagnosis of TB and monitoring the efficacy of therapy, including C-reactive protein (CRP), interferon-γ [IFN-γ], interleukin-6 [IL-6], tumor necrosis factor—α [TNF-α] or chemokine interferon-gamma inducible protein-10 (IP-10) [9,10,11,12]. This evidence concerns the gene TNF and tuberculosis.