Despite the lack of significant modulation of interleukin 1 Beta (IL-1β) and tumor necrosis factor-Alpha (TNFα) as activators of the canonical nuclear factor-κB (NF-κB) signaling pathway, both receptors (interleukin 1 receptor type 1-IL1R1 and TNFR1) were upregulated in DVT (Figure 5B). This evidence concerns the gene TNFRSF1A and deep vein thrombosis.