Other lncRNAs have been suggested as candidate biomarkers for HCC diagnosis in combination with α-fetoprotein (AFP): LINC00635 and ENSG00000258332.1 have been detected in serum exosomes of HCC patients and associated with poor prognosis [90], whereas SNGH1 has been shown to improve the accuracy of early diagnosis of HCC [91]. The gene discussed is AFP; the disease is hepatocellular carcinoma.