SLC2A4 and Hyperglycemia: Notably, in adipose and muscle tissue, GLUT4 expedites glucose uptake stimulated by insulin, and relatively low expression of GLUT4 correlates with less extensive insulin-mediated glucose uptake [71]; exacerbation of hyperglycemia could be the reason for this phenomenon, as indicated by the relatively high glucose intolerance observed in the executed IPGTTs.