Furthermore, highlighting the anti-apoptotic effect of DJ-1, we observed a positive correlation between DJ-1 and anti-apoptotic BCL2 in lung biopsies from pulmonary hypertensive patients (r = 0.886, p = 0.033, n = 6; Figure 3B) thereby, making DJ-1 an attractive therapeutic target in the treatment of pulmonary hypertension. Here, PARK7 is linked to pulmonary arterial hypertension.