Therefore, we extracted RNA from purified Vb5pos PD1pos and Vb5pos PD1neg CD4 T cells isolated from OT2 Tx recipient mice at tumor endpoint and analogously, from purified Vb5pos PD1pos and Vb5pos PD1neg CD8 T cells isolated from OT1 Tx recipient mice at tumor endpoint. The gene discussed is CD4; the disease is neoplasm.