Although O-glycosylated, sialofucosylated CD44v isoforms are the prevalent E-selectin ligands expressed by colon carcinoma cells, it has been shown that in hematopoietic cells, selectin ligand activity of CD44 is primarily associated with the N-glycosylated, sialofucosylated CD44s isoform [22,23]. This evidence concerns the gene SELE and colon carcinoma.