TCL1A also represses the expression of truncated receptor-type protein tyrosine phosphatase (PTPROt), a phosphatase expressed in naïve B cells that represses lymphoma in Eμ-TCL1A mice, and regulates BCR signals by modulating the activity of tyrosine kinases, including Lyn, Syk and ZAP70 [152,153,154,155]. Here, BCR is linked to lymphoma.