Additional mutant forms of EGFR, such as an EGFR fused with SEPT-14 (EGFR-SEPT14) [44,45], as well as EGFRs with a kinase domain duplication (EGFR-KDD) [46], have been identified in GBM, gastrointestinal and other tumors. The gene discussed is EGFR; the disease is glioblastoma.