In this study, we found that the expression of chemokine (C-C motif) ligand 7 (CCL7), also known as monocyte chemotactic protein 3, was enhanced in macrophages stimulated by human ovarian cancer cells as well as peritoneal macrophages from patients with ovarian cancer; CCL7 promoted the invasion of ovarian cancer cells. Here, CCL7 is linked to ovarian carcinoma.