CXCR4 and non-small cell lung carcinoma: It is supposed that NOX1 could mediate the expression of C-X-C chemokine receptor type 4 (CXCR4) and Matrix metallopeptidase 9 (MMP9) [407,408], which play an important role in the metastasis of non-small-cell lung carcinoma (NSCLC) [408,409].