Recently, Werion et al. reported that kidneys from patients with COVID-19 showed prominent tubular injury, with brush border loss, acute tubular necrosis, intraluminal debris, and a marked decrease of surface Megalin expression; electron microscopy showed viral particles resembling in vacuoles of the endoplasmic reticulum of proximal tubule cells [240]. The gene discussed is LRP2; the disease is COVID-19.