BDNF and coronary artery disorder: As previously shown [32], patients with CAD had significant lower plasma BDNF levels compared to HS (69.66 (10.0–264.4) pg/mL versus 208.9 (43.5–400.5) pg/mL, p < 0.0001) (Figure 1), and this difference was also maintained after adjustment for prior treatment and cardiovascular risk factors (p < 0.0005).