In T-cell lymphoblastic lymphoma/leukemia, LMO2 overexpression is to a lesser extent attributable to the presence of t(11;14)(p13;q11) or t(7;11)(q35;p13) involving LMO2 gene or to cryptic deletions of negative regulators of its transcription [20,21]. The gene discussed is LMO2; the disease is leukemia.