MC4R and obesity due to melanocortin 4 receptor deficiency: The data of multiple logistic regression analysis showed that odds of obesity, increased waist circumference, and metabolic syndrome adjusted for gender, energy intake and level of physical activity was by 1.8, 1.7, and 1.6 times higher in MC4R rs17782313 C allele carriers than in subjects with TT genotype (Table 5).