The cutaneous melanoma-associated mutations such as v-raf murine sarcoma viral oncogene homolog B1 (BRAF), neuroblastoma RAS viral oncogene homolog (NRAS) and neurofibromatosis type 1 (NF1) are not common in a UM, which are characterized by different oncogenic genes or mutations with a loss of function [6]. Here, BRAF is linked to cutaneous melanoma.