The studies assessing the impact of exposure to HTP and cardiovascular outcomes are rare, but suggest the decreased risk of cardiovascular disease and decrease adhesion of monotic cell to coronary endothelial cell, 11-dehydro-thromboxane B2 (a biomarker of platelet activation), 8-epi-prostaglandin F2α (a biomarker of oxidative stress), total cholesterol, C-reactive protein, platelets and leukocytes. The gene discussed is CRP; the disease is cardiovascular disorder.