CRP and cardiovascular disorder: On the other hand, studies assessing the impact of exposure to HTP and cardiovascular outcomes suggest a decreased risk of cardiovascular disease, as well as decreased adhesion of monotic cells to coronary endothelial cells, 11-dehydro-thromboxane B2 (a biomarker of platelet activation), 8-epi-prostaglandin F2α (a biomarker of oxidative stress), total cholesterol, C-reactive protein, platelets and leukocytes.