ICAM1 and endothelial dysfunction: In a study by Haziza et al. (2020), beneficial changes in lipid metabolism (total cholesterol and high and low-density cholesterol), endothelial dysfunction (soluble intercellular adhesion molecule-1), oxidative stress (8-epi-prostaglandin F2α) and cardiovascular risk factors (e.g., highly sensitive C-reactive protein) were observed in the mTHS group.