Statistically significant correlations were obtained between anti-GM1 IgM and IL-6, CRP, SLEDAI, anti-dsDNA, UACR; -GD1a and IL6; -GM2 and CRP, anti-dsDNA; -GM3 and CRP, anti-dsDNA in patients with SLE. This evidence concerns the gene CD40LG and systemic lupus erythematosus.