According to a study that targeted patients with presbycusis, whose discrimination threshold was higher than 40 dB sound pressure level (SPL) at 1kHz or higher, when the genotype of the GRM7 rs11928865 SNP was analyzed, the frequency of the T/T genotype was higher than that of the A/T genotype, and the T/T genotype had a 33% lower risk of tinnitus. The gene discussed is GRM7; the disease is Tinnitus.