FOXM1 overexpression in all cell types through a Rosa26-FOXM1b construct, when used in combination with a second tumor induction stimulus or oncogene, increased the number and size of lung adenomas [83]; increased the number, size, and proliferation of colon adenocarcinomas [84]; and accelerated the development of prostate adenocarcinomas [85]. The gene discussed is FOXM1; the disease is colon adenocarcinoma.