E-cadherin plays a dynamic role in ovarian cancer, where its overexpression is important for the growth and survival of ovarian cancer cells [245,246], its fragmentation is important for intraperitoneal metastasis [246,247], and its re-expression is a key part of mesenchymal-to-epithelial transition (MET) [245,248]. The gene discussed is CDH1; the disease is ovarian carcinoma.