ITGA6 and central nervous system cancer: In particular, the 12 genes most upregulated by the expression of ITGA6 in MES-GSCs correlated negatively with glioma patients’ survival, as shown by the Cox proportional hazards regression model (hazard ratio, 4.4; 95% confidence interval, 3.31–5.86; p = 1.89 × 10−24; Figure S7).