Moreover, they suggest a role for increased GR and MR availability in the dorsal hippocampus and reduced MR and GR availability in the ventral hippocampus in the development of PTSD-like behavioral responses by stressed rats (in both cases, the effects of stress in EBR are significantly different from the effects in MBR but not significantly different from the effects in PBR). The gene discussed is NR3C1; the disease is post-traumatic stress disorder.