Wang et al. [63] focused on nonfunctional pituitary adenomas (NFPAs) and demonstrated a lower expressions of folate receptor 1 (FOLR1) and epithelial cell adhesion molecules (EpCAM) in serum EVs derived from 10 patients suffering from invasive NFPAs compared to 10 healthy controls. This evidence concerns the gene EPCAM and pituitary gland adenoma.