ACHE and early-onset autosomal dominant Alzheimer disease: The extract of C. orchioides rhizome exhibited significant inhibitory effects on acetylcholinesterase, which suggested the potential of C. orchioides for the treatment of Alzheimer’s disease [72] G.K. Pratap et al. used bio-autograph and spectrophotometry to determine the anti-acetylcholinesterase activity of methanol extracts of C. orchioides in vitro.