Three hours after the beginning of the experiment, BT20 cells appeared to disrupt the VE-cadherin positive contacts between endothelial cells less frequently than SUM149PT cells (21% vs. 31.7%; n.s.), but showed more often VE-cadherin at the tumor cell-endothelial cell contacts (42.9% vs. 22.7%). Here, CDH5 is linked to neoplasm.