CXCL10 and infection: Key features of the SARS-CoV, MERS-CoV, and SARS-CoV-2 infections include commonalty of hyperinflammation and high levels of the chemokine CXCL10 (also referred to as interferon inducible protein-10; IP-10), an immunostimulatory host chemokine responsible for the recruitment of a variety of immune cells to sites of infection through interaction with its cellular receptor CXCR3.