The disease-free survival (DFS) and overall survival (OS) curves showed that GC patients with high transcriptional levels of SFRP1 (p = 0.014), SFRP2 (p = 0.039), and SFRP5 (p = 0.038) were significantly associated with short DFS, but patients with high transcriptional levels of SFRP3 or SFRP4 did not show such association (Figure 3A). This evidence concerns the gene FRZB and gastric cancer.