TGFB1 and renal fibrosis: Finally, it is worth noting that MRTF forms interactive networks with other major fibrogenic transcriptional regulators, including the TGFβ-controlled Smad proteins [19,20], and the Hippo pathway effectors, YAP and TAZ [21,22,23], all of which are involved in the pathogenesis of (renal) fibrosis.