To confirm our hypothesis, evaluating the presence of SELPLG in T and B-cell settings, we assessed that SELPLG is constantly more expressed in ALCL specimens both at the RNA level, according to GEP analyses, and at the protein level, as observed through the IHC in tissue microarray, in comparison with other T-cell lymphomas and controls. The gene discussed is SELPLG; the disease is T-cell non-Hodgkin lymphoma.