Analysis of apoptotic events in PE/CA-PJ49 and FaDu tumor lines, as well as in the HaCaT control cell line, was performed using the Annexin V-FITC Apoptosis Detection Kit I (BD Bioscience Pharmingen, USA), which ensures the double labeling of the cells with annexin V-FITC and propidium iodide (PI). The gene discussed is ANXA5; the disease is neoplasm.