Since the increased motility and invasion of tumour cells is usually preceded by epithelial-mesenchymal transition (EMT), i.e., a master event in tumour metastasis, we determined the effect of XN on the expression of E-cadherin, N-cadherin, α-E-catenin, vimentin, and Snail-1, which are the critical regulators of this phenomenon. This evidence concerns the gene CDH1 and neoplasm.