Periodontitis cases presented significantly differences regarding mean age, gender, race/ethnicity, education level, smoking status, family poverty ratio, Hcy mean levels, Hcy category levels, chronic medical conditions, diabetes mellitus, hypertension, BP (systolic BP (SBP) and diastolic BP (DBP)), C-reactive protein (CRP), periodontal inflamed surface area (PISA) and periodontal epithelial surface area (PESA) (p < 0.001). Here, CRP is linked to diabetes mellitus.