CRP and limb ischemia: GCA is characterized by ischaemic manifestations such as headache, jaw claudication, visual disturbances, and limb ischemia, and is accompanied by symptoms and signs of systemic inflammation that include fatigue, fever, weight loss, myalgia and increased inflammatory markers (erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and serum amyloid A (SAA)) [2,3,4].