DZIP1L and autosomal recessive polycystic kidney disease: Recently, using genome-wide analysis of SNPs, whole-exome sequencing, and Sanger sequencing, Lu and colleagues [37] established DZIP1L, located on chromosome 3 (3q22.1-q23) (Figure 2A), and encoding a 767-amino acid protein as a new gene related to ARPKD pathogenesis.