For examples, in locally advanced non-small cell lung cancer (NSCLC), a median serum sPD-L1 concentration of 67–68 pg/mL has been reported [66,122], whereas other studies indicated median sPD-L1 levels of 27 pg/mL [123], 84 pg/mL [124] and 176 pg/mL [125]. Here, SPDL1 is linked to non-small cell lung carcinoma.