We have investigated serum levels, diagnostic utility (sensitivity, specificity, predictive values of positive and negative test results), and power (ROC curve analysis) of all eotaxins (CCL11, CCL24, CCL26), their receptor (CCR3), comparative tumor markers (CA 19-9, CEA), and inflammatory parameter such as C-reactive protein (CRP) in colorectal cancer detection. This evidence concerns the gene CCR3 and colorectal cancer.