For instance, overexpression of the HOTAIR lncRNA correlates with cancers that are more aggressive [19,20,21,22,23,24,25], whereas MEG3 lncRNA may act as a tumor suppressor and its downregulation has been associated with the development of a variety of human cancer involving the liver, breast, uterus, and ovary [26]. The gene discussed is MEG3; the disease is cancer.