SNCA and Parkinson disease: Regarding other animal models, a recent study trying to obtain a rat model of PD and dopamine agonist induced impulsive behavior has shown that parkinsonian rats with partial bilateral nigrostriatal degeneration induced by human A53T α-synuclein over-expression within the SNc displayed a reduction of accuracy in the 5-Choice Serial Reaction time-task when compared to control rats or pre-parkinsonian status.