These cases present with a cytological profile similar to AML M3/M3v: AML with NPM1/t(5;17)(q35;q21), NUMA1/t(11;17)(q13;q21), PLZF/t(11;17)(q23;q21), PRKAR1A/del(17)(q21;q24)/t(17;17)(q21;q24), FIP1L1/t(4;17)(q12;q21), BCOR/t(X;17)(p11;q12), der(17) and t(3;17)(p25;q21). Here, ZBTB16 is linked to acute myeloid leukemia.