Four genes have recently been shown to be related to CHD: MTHFR (methylenetetrahydrofolate reductase), TBX1 (T-box transcription factor 1), TBX20 (T-Box transcription factor 20), and AXIN1 (axis inhibitor 1) [6,7,8,9]. This evidence concerns the gene TBX1 and coronary artery disorder.